Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05MAT
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| Former ID |
DNC007621
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| Drug Name |
1-adamantan-1-yl-3-(3-hydroxypropyl)urea
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| Synonyms |
CHEMBL242592; SMR000144635; 1-adamantan-1-yl-3-(3-hydroxypropyl)urea; AC1M3CD5; MLS000538598; MolPort-001-628-514; HMS2462I06; ZINC2882943; 1-(3-hydroxypropyl)-3-tricyclo[3.3.1.1~3,7~]dec-1-ylurea; STK207014; BDBM50223385; AKOS016321670; AKOS003366277; AKOS002318484; MCULE-4878985284; N-1-adamantyl-N'-(3-hydroxypropyl)urea; 1-(1-adamantyl)-3-(3-hydroxypropyl)urea; ST50766260
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H24N2O2
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| Canonical SMILES |
C1C2CC3CC1CC(C2)(C3)NC(=O)NCCCO
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| InChI |
1S/C14H24N2O2/c17-3-1-2-15-13(18)16-14-7-10-4-11(8-14)6-12(5-10)9-14/h10-12,17H,1-9H2,(H2,15,16,18)
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| InChIKey |
QADGUCFKHPQVSD-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Soluble epoxide hydrolase (EPHX2) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Peroxisome | ||||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Metapathway biotransformation | |||
| Arachidonate Epoxygenase / Epoxide Hydrolase | ||||
| Arachidonic acid metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1,3-disubstituted ureas functionalized with ether groups are potent inhibitors of the soluble epoxide hydrolase with improved pharmacokinetic prope... J Med Chem. 2007 Oct 18;50(21):5217-26. | |||
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