Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05MDE
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| Former ID |
DNC006568
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| Drug Name |
Cbz-Ile-Pro-Ala-LeuVSMe
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| Synonyms |
CHEMBL207670; Cbz-Ile-Pro-Ala-LeuVSMe
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C30H46N4O7S
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| Canonical SMILES |
CCC(C)C(C(=O)N1CCCC1C(=O)NC(C)C(=O)NC(CC(C)C)C=CS(=O)(=O)C)NC(=O)OCC2=CC=CC=C2
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| InChI |
1S/C30H46N4O7S/c1-7-21(4)26(33-30(38)41-19-23-12-9-8-10-13-23)29(37)34-16-11-14-25(34)28(36)31-22(5)27(35)32-24(18-20(2)3)15-17-42(6,39)40/h8-10,12-13,15,17,20-22,24-26H,7,11,14,16,18-19H2,1-6H3,(H,31,36)(H,32,35)(H,33,38)/b17-15+/t21-,22-,24+,25-,26-/m0/s1
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| InChIKey |
QUUKVNWZLKQWBG-DHJGLREUSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cathepsin S (CTSS) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Lysosome | |||
| Phagosome | ||||
| Antigen processing and presentation | ||||
| Tuberculosis | ||||
| NetPath Pathway | Leptin Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| Reactome | Endosomal/Vacuolar pathway | |||
| Degradation of the extracellular matrix | ||||
| Trafficking and processing of endosomal TLR | ||||
| Assembly of collagen fibrils and other multimeric structures | ||||
| MHC class II antigen presentation | ||||
| WikiPathways | Class I MHC mediated antigen processing & presentation | |||
| Trafficking and processing of endosomal TLR | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Optimization of subsite binding to the beta5 subunit of the human 20S proteasome using vinyl sulfones and 2-keto-1,3,4-oxadiazoles: syntheses and c... J Med Chem. 2006 May 18;49(10):2953-68. | |||
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