Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D05NAR
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| Former ID |
DNC012908
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| Drug Name |
Allyl 4-(aminosulfonyl)benzoate
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| Synonyms |
CHEMBL381455; 103204-31-5; Benzoic acid, 4-(aminosulfonyl)-, 2-propenyl ester; allyl 4-(aminosulfonyl)benzoate; ACMC-20m632; SCHEMBL6705334; CTK0G7183; DTXSID90468211; VWKMDRWBZTWKNM-UHFFFAOYSA-N; BDBM50175049; 4-Sulfamoyl-benzoic acid allyl ester
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H11NO4S
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| Canonical SMILES |
C=CCOC(=O)C1=CC=C(C=C1)S(=O)(=O)N
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| InChI |
1S/C10H11NO4S/c1-2-7-15-10(12)8-3-5-9(6-4-8)16(11,13)14/h2-6H,1,7H2,(H2,11,13,14)
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| InChIKey |
VWKMDRWBZTWKNM-UHFFFAOYSA-N
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| CAS Number |
CAS 103204-31-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and structure-activity relationships of novel benzene sulfonamides with potent binding affinity for bovine carbonic anhydrase II. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5429-33. | |||
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