Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05RGO
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| Former ID |
DNC014228
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| Drug Name |
H-Pro-Phe-Phe-NH2
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| Synonyms |
CHEMBL591489; H-Pro-Phe-Phe-NH2
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C23H28N4O3
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| Canonical SMILES |
C1CC(NC1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CC3=CC=CC=C3)C(=O)N
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| InChI |
1S/C23H28N4O3/c24-21(28)19(14-16-8-3-1-4-9-16)26-23(30)20(15-17-10-5-2-6-11-17)27-22(29)18-12-7-13-25-18/h1-6,8-11,18-20,25H,7,12-15H2,(H2,24,28)(H,26,30)(H,27,29)/t18-,19-,20-/m0/s1
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| InChIKey |
GQTQFZUTXSDLLQ-UFYCRDLUSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Substance-P receptor (TACR1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Measles | ||||
| Panther Pathway | CCKR signaling map ST | |||
| Reactome | G alpha (q) signalling events | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Spinal Cord Injury | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of dipeptides with high affinity to the specific binding site for substance P1-7. J Med Chem. 2010 Mar 25;53(6):2383-9. | |||
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