Drug Information
Drug General Information | Top | |||
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Drug ID |
D05RGW
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Former ID |
DNC002355
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Drug Name |
Methimepip
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Synonyms |
Methimepip; GTPL1254; CHEMBL175782; SCHEMBL8320104; BDBM22909; ZINC6716245; AKOS027324257; 4-(3H-imidazol-4-ylmethyl)-1-methylpiperidine; 4-(1H-imidazol-5-ylmethyl)-1-methylpiperidine; L009044
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C10H17N3
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Canonical SMILES |
CN1CCC(CC1)CC2=CN=CN2
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InChI |
1S/C10H17N3/c1-13-4-2-9(3-5-13)6-10-7-11-8-12-10/h7-9H,2-6H2,1H3,(H,11,12)
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InChIKey |
KIAVPENCSGKVQP-UHFFFAOYSA-N
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CAS Number |
CAS 151070-80-3
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Histamine H3 receptor (H3R) | Target Info | Agonist | [2] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Reactome | Histamine receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | Monoamine Transport | |||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1254). | |||
REF 2 | The histamine H3 receptor: from gene cloning to H3 receptor drugs. Nat Rev Drug Discov. 2005 Feb;4(2):107-20. |
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