Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D05RZI
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| Former ID |
DIB013157
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| Drug Name |
AA-193
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| Synonyms |
AA-193; 107804-48-8; Furo[2,3-g]-1,2-benzisoxazole-7-carboxylicacid, 5-chloro-7,8-dihydro-3-phenyl-; AC1OCEWV; ACMC-20mb6x; CHEMBL93997; SCHEMBL10512834; CTK0H6407; AKOS030601198; 5-chloro-3-phenyl-7,8-dihydrofuro[2,3-g][1,2]benzoxazole-7-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Hyperuricaemia [ICD-11: 5C55.Y] | Discontinued in Phase 2 | [1] | |
| Company |
Chugai Pharmaceutical Co Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C16H10ClNO4
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| Canonical SMILES |
C1C(OC2=C(C=C3C(=C21)ON=C3C4=CC=CC=C4)Cl)C(=O)O
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| InChI |
1S/C16H10ClNO4/c17-11-6-9-13(8-4-2-1-3-5-8)18-22-14(9)10-7-12(16(19)20)21-15(10)11/h1-6,12H,7H2,(H,19,20)
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| InChIKey |
RVKIPRIYUGLRFF-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glucose transporter type 9 (GLUT9) | Target Info | Modulator | [2] |
| References | Top | |||
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| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003058) | |||
| REF 2 | Uricosurics inhibit urate transporter in rat renal brush border membrane vesicles. Eur J Pharmacol. 1990 Oct 23;187(3):303-12. | |||
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