Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D05SNS
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| Former ID |
DNC003610
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| Drug Name |
2-(2-Hydroxycarbamoyl-ethyl)-pentanedioic acid
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| Synonyms |
CHEMBL63454; 475653-52-2; 2-(2-Hydroxycarbamoyl-ethyl)-pentanedioic acid; SCHEMBL13996820; CTK1C7211; DTXSID40609753; BDBM50129195; 2-[3-Oxo-3-(hydroxyamino)propyl]pentanedioic acid; 2-[3-(Hydroxyamino)-3-oxopropyl]pentanedioic acid; Pentanedioic acid, 2-[3-(hydroxyamino)-3-oxopropyl]-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C8H13NO6
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| Canonical SMILES |
C(CC(=O)NO)C(CCC(=O)O)C(=O)O
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| InChI |
1S/C8H13NO6/c10-6(9-15)3-1-5(8(13)14)2-4-7(11)12/h5,15H,1-4H2,(H,9,10)(H,11,12)(H,13,14)
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| InChIKey |
HTZIUDNKEYUDDE-UHFFFAOYSA-N
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| CAS Number |
CAS 475653-52-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate carboxypeptidase II (GCPII) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
| Metabolic pathways | ||||
| Vitamin digestion and absorption | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| TNFalpha Signaling Pathway | ||||
| Reactome | Amino acid synthesis and interconversion (transamination) | |||
| WikiPathways | One Carbon Metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of hydroxamate-Based inhibitors of glutamate carboxypeptidase II. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2097-100. | |||
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