Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05STL
|
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| Former ID |
DNCL002012
|
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| Drug Name |
ARRY-502
|
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| Indication | Allergic asthma [ICD-11: CA23.0; ICD-10: J45.0] | Phase 2 | [1] | |
| Company |
Array BioPharma
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C26H23Cl2NO6
|
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| Canonical SMILES |
COC1=C(C=CC(=C1)Cl)CCNC(=O)C2=CC=C(C=C2)OC3=C(C=C4C(CCOC4=C3)C(=O)O)Cl
|
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| InChI |
1S/C26H23Cl2NO6/c1-33-22-12-17(27)5-2-15(22)8-10-29-25(30)16-3-6-18(7-4-16)35-24-14-23-20(13-21(24)28)19(26(31)32)9-11-34-23/h2-7,12-14,19H,8-11H2,1H3,(H,29,30)(H,31,32)/t19-/m0/s1
|
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| InChIKey |
QIDYUNXQPQEJEC-IBGZPJMESA-N
|
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| CAS Number |
CAS 1202891-16-4
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin D2 receptor 2 (PTGDR2) | Target Info | Modulator | [2] |
| Reactome | Prostanoid ligand receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01561690) A Study of ARRY-502 in Patients With Persistent Asthma. U.S. National Institutes of Health. | |||
| REF 2 | Clinical pipeline report, company report or official report of Array BioPharma (Drug: ARRY-502). | |||
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