Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05TMJ
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| Former ID |
DNC006767
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| Drug Name |
1-phenyl-3-(2-(pyridin-2-yl)quinazolin-4-yl)urea
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| Synonyms |
CHEMBL423311; 1-phenyl-3-(2-(pyridin-2-yl)quinazolin-4-yl)urea; BDBM50088476; 1-[2-(2-Pyridyl)-4-quinazolinyl]-3-phenylurea
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C20H15N5O
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| Canonical SMILES |
C1=CC=C(C=C1)NC(=O)NC2=NC(=NC3=CC=CC=C32)C4=CC=CC=N4
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| InChI |
1S/C20H15N5O/c26-20(22-14-8-2-1-3-9-14)25-18-15-10-4-5-11-16(15)23-19(24-18)17-12-6-7-13-21-17/h1-13H,(H2,22,23,24,25,26)
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| InChIKey |
XZUXPDFYRHJJLN-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A3 receptor (ADORA3) | Target Info | Inhibitor | [1] |
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models. J Med Chem. 2006 Jul 13;49(14):4085-97. | |||
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