Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05VGS
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| Former ID |
DCL001137
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| Drug Name |
ALB-127158(a)
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| Indication | Obesity [ICD-11: 5B81; ICD-10: E66; ICD-9: 278] | Terminated | [1] | |
| Company |
Albany Molecular Research Inc.
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| Structure |
 |
Download2D MOL |
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| Formula |
C23H21FN4O2
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| Canonical SMILES |
CN1C2=C(CNCC2)C3=C1C=C(C=C3)N4C=CC(=CC4=O)OCC5=NC=C(C=C5)F
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| InChI |
1S/C23H21FN4O2/c1-27-21-6-8-25-13-20(21)19-5-4-17(10-22(19)27)28-9-7-18(11-23(28)29)30-14-16-3-2-15(24)12-26-16/h2-5,7,9-12,25H,6,8,13-14H2,1H3
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| InChIKey |
VUUUHLIHQHVLLE-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Melanin-concentrating hormone receptor 1 (MCHR1) | Target Info | Antagonist | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of Albany Molecular Research (2011). | |||
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