Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D05WZF
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| Former ID |
DNC005106
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| Drug Name |
P2,P3 Ketoamide derivative
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| Synonyms |
CHEMBL186650; P2,P3 Ketoamide derivative; SCHEMBL14260244; AAYZJXOZLLKNGZ-DEOSSOPVSA-N; BDBM50152530
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C28H38FN5O6S
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| Canonical SMILES |
CN(C)S(=O)(=O)NCCCCC(C(=O)C(=O)NCC1=CN=CC=C1)NC(=O)OCC2(CCC2)CC3=CC=C(C=C3)F
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| InChI |
1S/C28H38FN5O6S/c1-34(2)41(38,39)32-16-4-3-8-24(25(35)26(36)31-19-22-7-5-15-30-18-22)33-27(37)40-20-28(13-6-14-28)17-21-9-11-23(29)12-10-21/h5,7,9-12,15,18,24,32H,3-4,6,8,13-14,16-17,19-20H2,1-2H3,(H,31,36)(H,33,37)/t24-/m0/s1
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| InChIKey |
AAYZJXOZLLKNGZ-DEOSSOPVSA-N
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Potent and selective P2-P3 ketoamide inhibitors of cathepsin K with good pharmacokinetic properties via favorable P1', P1, and/or P3 substitutions. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4897-902. | |||
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