Drug Information
Drug General Information | Top | |||
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Drug ID |
D05WZK
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Former ID |
DIB019880
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Drug Name |
frescolat ML
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Synonyms |
(-)-menthyl lactate
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C13H24O3
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Canonical SMILES |
CC1CCC(C(C1)OC(=O)C(C)O)C(C)C
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InChI |
1S/C13H24O3/c1-8(2)11-6-5-9(3)7-12(11)16-13(15)10(4)14/h8-12,14H,5-7H2,1-4H3/t9-,10?,11+,12-/m1/s1
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InChIKey |
UJNOLBSYLSYIBM-SGUBAKSOSA-N
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CAS Number |
CAS 61597-98-6
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PubChem Compound ID | ||||
PubChem Substance ID |
8187905, 10544020, 14822858, 16387231, 25628216, 43119320, 50065637, 53800999, 76756494, 90454690, 104325093, 126622861, 126654340, 126685958, 135020134, 136903903, 142938834, 143500803, 152103505, 152164709, 152246177, 152250011, 163412428, 164239507, 184551574, 196111352, 226657982, 241101983, 246678956, 250144653
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Target and Pathway | Top | |||
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Target(s) | Long transient receptor potential channel 8 (TRPM8) | Target Info | Activator | [2] |
KEGG Pathway | Inflammatory mediator regulation of TRP channels | |||
Reactome | TRP channels |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2466). | |||
REF 2 | Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br J Pharmacol. 2004 Feb;141(4):737-45. |
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