Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05YAD
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| Drug Name |
PMID25656651-Compound-11c
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| Drug Type |
Small molecular drug
|
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| Indication | Chronic myeloid leukaemia [ICD-11: 2A20; ICD-10: D47.7] | Patented | [1] | |
| Company |
CURIS, INC
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C23H28ClN7O3S
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| Canonical SMILES |
CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=NC(=NC(=C3)NCCCCCCC(=O)NO)C
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| InChI |
1S/C23H28ClN7O3S/c1-14-8-7-9-16(24)21(14)30-22(33)17-13-26-23(35-17)29-19-12-18(27-15(2)28-19)25-11-6-4-3-5-10-20(32)31-34/h7-9,12-13,34H,3-6,10-11H2,1-2H3,(H,30,33)(H,31,32)(H2,25,26,27,28,29)
|
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| InChIKey |
UHHSKEMLNIATAI-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fusion protein Bcr-Abl (Bcr-Abl) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Fusion protein Bcr-Abl (Bcr-Abl) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Bcr-Abl tyrosine kinase inhibitors: a patent review.Expert Opin Ther Pat. 2015 Apr;25(4):397-412. | |||
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