Drug Information
Drug General Information | Top | |||
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Drug ID |
D06DWQ
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Former ID |
DIB004230
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Drug Name |
TOPIXANTRONE HYDROCHLORIDE
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Synonyms |
Topixantrone hydrochloride; SCHEMBL1418986; Topixantrone hydrochloride < Prop INNM; BBR-3409 (dimaleate); 5-[2-(Dimethylamino)ethylamino]-2-[2-(2-hydroxyethylamino)ethyl]indazolo[4,3-gh]isoquinolin-6(2H)-one dihydrochloride
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Drug Type |
Small molecular drug
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Indication | Gastric adenocarcinoma [ICD-11: 2B72; ICD-9: 151] | Discontinued in Phase 2 | [1] | |
Structure |
Download2D MOL |
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Formula |
C21H28Cl2N6O2
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Canonical SMILES |
CN(C)CCNC1=C2C3=C(C=C1)N(N=C3C4=C(C2=O)C=CN=C4)CCNCCO.Cl.Cl
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InChI |
1S/C21H26N6O2.2ClH/c1-26(2)10-8-24-16-3-4-17-19-18(16)21(29)14-5-6-23-13-15(14)20(19)25-27(17)11-7-22-9-12-28;;/h3-6,13,22,24,28H,7-12H2,1-2H3;2*1H
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InChIKey |
CQZQVNJGECUKMB-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Human Deoxyribonucleic acid (hDNA) | Target Info | Inhibitor | [2] |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015071) | |||
REF 2 | Clinical pipeline report, company report or official report of CTI BioPharma. |
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