Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06GGT
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| Former ID |
DNC001564
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| Drug Name |
MCL-1-specific antisense oligonucleotide + nilotinib (AMN107)
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| Synonyms |
641571-10-0; UNII-F41401512X; Nilotinib (AMN-107); CHEMBL255863; CHEBI:52172; C28H22F3N7O; HHZIURLSWUIHRB-UHFFFAOYSA-N; NSC747599
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| Drug Type |
Combination drug (Antisense drug)
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| Indication | Systemic mastocytosis [ICD-11: 2A21.0; ICD-9: 202.6, 757.33] | Investigative | [1] | |
| Therapeutic Class |
Antisense
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Mcl-1 messenger RNA (MCL-1 mRNA) | Target Info | . | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Design and development of antisense drugs. Expert Opin. Drug Discov. 2008 3(10):1189-1207. | |||
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