Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06GQO
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| Former ID |
DNC004502
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| Drug Name |
N-Butyl-N'-(4-methyl-benzoyl)-guanidine
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| Synonyms |
CHEMBL432963; SCHEMBL4629393; BDBM50107019; 1-Butyl-2-(4-methylbenzoyl)guanidine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H19N3O
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| Canonical SMILES |
CCCCN=C(N)NC(=O)C1=CC=C(C=C1)C
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| InChI |
1S/C13H19N3O/c1-3-4-9-15-13(14)16-12(17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H3,14,15,16,17)
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| InChIKey |
ALSYKIYWLYFZIK-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated sodium channel alpha Nav1.5 (SCN5A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Adrenergic signaling in cardiomyocytes | |||
| Pathwhiz Pathway | Muscle/Heart Contraction | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Cardiac Progenitor Differentiation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Solution-phase, parallel synthesis and pharmacological evaluation of acylguanidine derivatives as potential sodium channel blockers. Bioorg Med Chem Lett. 2001 Dec 17;11(24):3151-5. | |||
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