Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06GZW
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| Former ID |
DIB007447
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| Drug Name |
PEGylated leptin
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| Synonyms |
PEG-Leptin; PEGylated leptin (obesity/type 1 diabetes); PEGylated leptin (obesity/type 1 diabetes), Ambrx
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| Indication | Obesity [ICD-11: 5B81; ICD-10: E66; ICD-9: 278] | Investigative | [1] | |
| Company |
Ambrx Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Leptin receptor (LEPR) | Target Info | Modulator | [1] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Neuroactive ligand-receptor interaction | ||||
| AMPK signaling pathway | ||||
| Jak-STAT signaling pathway | ||||
| Adipocytokine signaling pathway | ||||
| Non-alcoholic fatty liver disease (NAFLD) | ||||
| Pathway Interaction Database | Signaling events mediated by PTP1B | |||
| WikiPathways | Leptin signaling pathway | |||
| AMPK Signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1712). | |||
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