Drug Information
Drug General Information | Top | |||
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Drug ID |
D06HCD
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Former ID |
DIB005917
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Drug Name |
SM-6586
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Drug Type |
Small molecular drug
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Indication | Hypertension [ICD-11: BA00-BA04; ICD-9: 401] | Discontinued in Phase 1 | [1] | |
Company |
Sumitomo Pharmaceuticals Co Ltd
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Structure |
Download2D MOL |
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Formula |
C26H27N5O5
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Canonical SMILES |
CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC(=CC=C2)[N+](=O)[O-])C3=NC(=NO3)CN(C)CC4=CC=CC=C4
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InChI |
1S/C26H27N5O5/c1-16-22(25-28-21(29-36-25)15-30(3)14-18-9-6-5-7-10-18)24(23(17(2)27-16)26(32)35-4)19-11-8-12-20(13-19)31(33)34/h5-13,24,27H,14-15H2,1-4H3
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InChIKey |
HHVCXSOKQHQGFB-UHFFFAOYSA-N
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CAS Number |
CAS 103898-38-0
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Calcium channel unspecific (CaC) | Target Info | Antagonist | [2] |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002576) | |||
REF 2 | Calcium channel blocking properties of SM-6586 in rat heart and brain as assessed by radioligand binding assay. Jpn J Pharmacol. 1993 Oct;63(2):165-9. |
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