Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06HFI
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| Former ID |
DIB002075
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| Drug Name |
L-ornithine phenylacetate
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| Synonyms |
L-ornthine phenylacetate; OCR-002; UCL-L1V; L-ornithine phenylacetate (injectable, acute hepatic encephalopathy); Nitrogen metabolism modulator (injectable, AHE), Ocera; Nitrogen metabolism modulator (injectable, acute hepatic encephalopathy), Ocera; Nitrogen metabolism modulator (injectable, acute hepatic encephalopathy), UCL; Nitrogen metabolism modulator (injectable, hyperammonemia), Ocera; L-ornithine phenylacetate (injectable, AHE), Ocera; L-ornithine phenylacetate (injectable, acute hepatic encephalopathy), Ocera; L-ornithine phenylacetate (injectable, hyperammonemia), Ocera
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| Drug Type |
Small molecular drug
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| Indication | Acute liver failure [ICD-11: DB91] | Phase 2 | [1] | |
| Company |
Ocera therapeutics
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| Structure |
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Download2D MOL |
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| Formula |
C13H20N2O4
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| Canonical SMILES |
C1=CC=C(C=C1)CC(=O)O.C(CC(C(=O)O)N)CN
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| InChI |
1S/C8H8O2.C5H12N2O2/c9-8(10)6-7-4-2-1-3-5-7;6-3-1-2-4(7)5(8)9/h1-5H,6H2,(H,9,10);4H,1-3,6-7H2,(H,8,9)/t;4-/m.0/s1
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| InChIKey |
LRSYFEZBIMVWRY-VWMHFEHESA-N
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| CAS Number |
CAS 952154-79-9
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01634230) Emergency Use of OCR-002 in Acute Liver Failure. U.S. National Institutes of Health. | |||
| REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | |||
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