Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06LDC
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| Former ID |
DIB009985
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| Drug Name |
Palonidipine hydrochloride
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| Synonyms |
Palonidipine; TC-81
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| Drug Type |
Small molecular drug
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| Indication | Hypertension [ICD-11: BA00-BA04; ICD-9: 401] | Discontinued in Preregistration | [1] | |
| Company |
Teijin Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C29H35ClFN3O6
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| Canonical SMILES |
CC1=C(C(C(=C(N1)C)C(=O)OCC(C)(C)CN(C)CC2=CC=CC=C2)C3=C(C=CC(=C3)[N+](=O)[O-])F)C(=O)OC.Cl
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| InChI |
1S/C29H34FN3O6.ClH/c1-18-24(27(34)38-6)26(22-14-21(33(36)37)12-13-23(22)30)25(19(2)31-18)28(35)39-17-29(3,4)16-32(5)15-20-10-8-7-9-11-20;/h7-14,26,31H,15-17H2,1-6H3;1H
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| InChIKey |
OQHXRVQARZHYGQ-UHFFFAOYSA-N
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| CAS Number |
CAS 96515-74-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium channel unspecific (CaC) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001157) | |||
| REF 2 | Effect of palonidipine hydrochloride (TC-81), a novel calcium antagonist, on the canine coronary artery. Nihon Yakurigaku Zasshi. 1993 Jul;102(1):23-33. | |||
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