Drug Information
Drug General Information | Top | |||
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Drug ID |
D06MMU
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Former ID |
DIB002689
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Drug Name |
LM-CD45
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Synonyms |
Anti-CD45, Baxter; Anti-CD45, Cantab
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Drug Type |
Antibody
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Indication | Transplant rejection [ICD-11: NE84; ICD-9: 279.5, 996] | Phase 1 | [1] | |
Company |
Cantab Biopharmaceuticals Ltd
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Target and Pathway | Top | |||
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Target(s) | Leukocyte common antigen (PTPRC) | Target Info | . | [2] |
KEGG Pathway | Cell adhesion molecules (CAMs) | |||
T cell receptor signaling pathway | ||||
Fc gamma R-mediated phagocytosis | ||||
Primary immunodeficiency | ||||
NetPath Pathway | TCR Signaling Pathway | |||
IL2 Signaling Pathway | ||||
Panther Pathway | B cell activation | |||
JAK/STAT signaling pathway | ||||
T cell activation | ||||
Pathway Interaction Database | BCR signaling pathway | |||
TCR signaling in naï | ||||
TCR signaling in naï | ||||
CXCR4-mediated signaling events | ||||
Reactome | Phosphorylation of CD3 and TCR zeta chains | |||
Other semaphorin interactions | ||||
WikiPathways | Interferon type I signaling pathways | |||
EPO Receptor Signaling | ||||
B Cell Receptor Signaling Pathway | ||||
TCR signaling | ||||
Semaphorin interactions |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT01678443) Monoclonal Antibody Therapy Before Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoid Malignancies. U.S. National Institutes of Health. | |||
REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002932) |
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