Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06NGQ
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| Former ID |
DNC011293
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| Drug Name |
5-Benzyloxytryptamine
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| Synonyms |
5-Benzyloxytryptamine; 20776-45-8; 2-(5-Benzyloxy-1H-indol-3-yl)-ethylamine; 5-Benzyloxytriptamine; 2-[5-(benzyloxy)-1H-indol-3-yl]ethanamine; 3-(2-aminoethyl)-5-benzyloxyindole; 5-BT; CHEMBL1288652; 2-(5-(Benzyloxy)-1H-indol-3-yl)ethanamine; WKPDXBXNJWWWGQ-UHFFFAOYSA-N; 5-Benzyloxy-3-(2-ethylamino)indole hydrochloride; 1H-Indole-3-ethanamine,5-(phenylmethoxy)-; 1H-Indole-3-ethanamine, 5-(phenylmethoxy)-; B-2100; 2-[5-(benzyloxy)-1H-indol-3-yl]ethanamine hydrochloride; 2-[5-(phenylmethoxy)indol-3-yl]ethylamine; EINECS 244-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C17H18N2O
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| Canonical SMILES |
C1=CC=C(C=C1)COC2=CC3=C(C=C2)NC=C3CCN
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| InChI |
1S/C17H18N2O/c18-9-8-14-11-19-17-7-6-15(10-16(14)17)20-12-13-4-2-1-3-5-13/h1-7,10-11,19H,8-9,12,18H2
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| InChIKey |
WKPDXBXNJWWWGQ-UHFFFAOYSA-N
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| CAS Number |
CAS 20776-45-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3132127, 4765425, 10223745, 11133553, 15269336, 24338245, 26662963, 44420676, 47440757, 47589473, 48110932, 49746873, 49983305, 57334625, 57567420, 57638495, 77774294, 85209583, 88822616, 96022649, 104399711, 106223811, 118055384, 121280615, 123095186, 123110399, 124618449, 124952847, 125147902, 125565577, 126533627, 126665332, 127354857, 129595179, 134348498, 135047120, 135232248, 135310052, 135560499, 135649825, 136350274, 137018524, 143264137, 143394152, 143535747, 160998562, 162813389, 163577619, 165245693, 169190668
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Long transient receptor potential channel 8 (TRPM8) | Target Info | Inhibitor | [2] |
| KEGG Pathway | Inflammatory mediator regulation of TRP channels | |||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 265). | |||
| REF 2 | 5-benzyloxytryptamine as an antagonist of TRPM8. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7076-9. | |||
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