Drug Information
Drug General Information | Top | |||
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Drug ID |
D06NIT
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Former ID |
DIB012770
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Drug Name |
PF-4181366
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Synonyms |
PDE9A inhibitor (cognitive deficit), Pfizer
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Drug Type |
Small molecular drug
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Indication | Cognitive impairment [ICD-11: 6D71; ICD-10: F06.7] | Investigative | [1] | |
Company |
Pfizer Inc
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Structure |
Download2D MOL |
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Formula |
C24H27N7O
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Canonical SMILES |
CC1CN(CC1C2=NC3=C(C=NN3C4CCCC4)C(=O)N2)CC5=CC6=NC=CN=C6C=C5
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InChI |
1S/C24H27N7O/c1-15-12-30(13-16-6-7-20-21(10-16)26-9-8-25-20)14-19(15)22-28-23-18(24(32)29-22)11-27-31(23)17-4-2-3-5-17/h6-11,15,17,19H,2-5,12-14H2,1H3,(H,28,29,32)/t15-,19-/m1/s1
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InChIKey |
SNCRCEGCQVMUBS-DNVCBOLYSA-N
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CAS Number |
CAS 1082743-32-5
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Phosphodiesterase 9 (PDE9) | Target Info | Inhibitor | [1] |
KEGG Pathway | Purine metabolism | |||
Pathway Interaction Database | Regulation of Androgen receptor activity | |||
Reactome | cGMP effects |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1309). |
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