Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06PVO
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| Former ID |
DNC007516
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| Drug Name |
4-phenyl-1-(1-phenylpropyl)piperidin-4-ol
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| Synonyms |
CHEMBL433814; 4-phenyl-1-(1-phenylpropyl)piperidin-4-ol; SCHEMBL9520650
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C20H25NO
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| Canonical SMILES |
CCC(C1=CC=CC=C1)N2CCC(CC2)(C3=CC=CC=C3)O
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| InChI |
1S/C20H25NO/c1-2-19(17-9-5-3-6-10-17)21-15-13-20(22,14-16-21)18-11-7-4-8-12-18/h3-12,19,22H,2,13-16H2,1H3
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| InChIKey |
YUOJNJIUXXIUHY-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nociceptin receptor (OPRL1) | Target Info | Inhibitor | [1] |
| Opioid receptor kappa (OPRK1) | Target Info | Inhibitor | [1] | |
| Opioid receptor mu (MOP) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Estrogen signaling pathway | ||||
| Morphine addiction | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Opioid prodynorphin pathway | ||||
| Enkephalin release | ||||
| Pathway Interaction Database | IL4-mediated signaling events | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| TCR Signaling Pathway | ||||
| Opioid Signalling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Bioorg Med Chem Lett. 2007 Jun 1;17(11):3023-7. Epub 2007 Mar 23.Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 1. | |||
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