Drug Information
Drug General Information | Top | |||
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Drug ID |
D06PZN
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Former ID |
DNC000959
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Drug Name |
Mosapride
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Synonyms |
Mosapride; 112885-41-3; 4-amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide; Mosapride [INN]; CHEMBL60889; Mosapride (INN); 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]benzamide; AK-41276; 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide; Q-201413; 4-amino-5-chloro-2-ethoxy-N-({4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl)benzamide
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C21H25ClFN3O3
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Canonical SMILES |
CCOC1=CC(=C(C=C1C(=O)NCC2CN(CCO2)CC3=CC=C(C=C3)F)Cl)N
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InChI |
1S/C21H25ClFN3O3/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27)
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InChIKey |
YPELFRMCRYSPKZ-UHFFFAOYSA-N
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CAS Number |
CAS 112885-41-3
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PubChem Compound ID | ||||
PubChem Substance ID |
10238548, 14856046, 29216210, 29300427, 47434920, 48254040, 49875381, 50110109, 53346072, 57339567, 85209635, 90452581, 92720568, 93374710, 93626124, 96024924, 103250420, 103923914, 104408671, 117843401, 125324809, 125338080, 126607121, 126619873, 126648433, 126666115, 129828067, 131294814, 131294815, 131813325, 134340239, 135134188, 135650625, 135683234, 136373748, 137249282, 137541651, 143504192, 144108846, 160809785, 162035093, 162181032, 163088239, 164035874, 164175206, 164814860, 166236538, 172090760, 172842270, 174006284
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ChEBI ID |
CHEBI:94373
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Target and Pathway | Top | |||
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Target(s) | 5-HT 4 receptor (HTR4) | Target Info | Agonist | [1] |
KEGG Pathway | Calcium signaling pathway | |||
cAMP signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Serotonergic synapse | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
5HT4 type receptor mediated signaling pathway | ||||
Pathwhiz Pathway | Excitatory Neural Signalling Through 5-HTR 4 and Serotonin | |||
Reactome | Serotonin receptors | |||
G alpha (s) signalling events | ||||
WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | The in vitro pharmacological profile of TD-5108, a selective 5-HT(4) receptor agonist with high intrinsic activity. Naunyn Schmiedebergs Arch Pharmacol. 2008 Jul;378(1):125-37. |
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