Drug Information
Drug General Information | Top | |||
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Drug ID |
D06QLG
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Former ID |
DNC014120
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Drug Name |
Tyr-D-Ala-Gly-NMePhe
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Synonyms |
CHEMBL583426; Tyr-D-Ala-Gly-NMePhe
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C21H26N4O4
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Canonical SMILES |
CC(C(=O)NCC(=O)N(C)C1=CC=CC=C1)NC(=O)C(CC2=CC=C(C=C2)O)N
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InChI |
1S/C21H26N4O4/c1-14(24-21(29)18(22)12-15-8-10-17(26)11-9-15)20(28)23-13-19(27)25(2)16-6-4-3-5-7-16/h3-11,14,18,26H,12-13,22H2,1-2H3,(H,23,28)(H,24,29)/t14-,18+/m1/s1
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InChIKey |
OPRBFENCQHCQFV-KDOFPFPSSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Opioid receptor mu (MOP) | Target Info | Inhibitor | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Estrogen signaling pathway | ||||
Morphine addiction | ||||
NetPath Pathway | TCR Signaling Pathway | |||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
Enkephalin release | ||||
Pathway Interaction Database | IL4-mediated signaling events | |||
Reactome | Peptide ligand-binding receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | TCR Signaling Pathway | |||
GPCRs, Class A Rhodopsin-like | ||||
Peptide GPCRs | ||||
Opioid Signalling | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Discovery of dermorphin-based affinity labels with subnanomolar affinity for mu opioid receptors. J Med Chem. 2009 Dec 10;52(23):7372-5. |
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