Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06RBJ
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| Former ID |
DIB013073
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| Drug Name |
DIPROTEVERINE HYDROCHLORIDE
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| Synonyms |
UNII-T587ZFV6UM; T587ZFV6UM; Isoquinoline, 3,4-dihydro-6,7-bis(1-methylethoxy)-1-((3,4-diethoxyphenyl)methyl)-, hydrochloride; 69373-88-2; 1-(3',4'-Diethoxybenzyl)-6,7-diisoprooxy-3,4-dihydroisoquinoline hydrochloride; DIPROTEVERINE HYDROCHLORIDE; AC1MHK6D; SCHEMBL7313181; DTXSID30219461; AWQPJKUSDUHYIX-UHFFFAOYSA-N; 69373-95-1 (Parent); LS-85505; 1-(3'4'-diethoxybenzyl)-6,7-diisopropoxy-3,4-dihydroisoquinoline hydrochloride; 1-[(3,4-diethoxyphenyl)methyl]-6,7-di(propan-2-yloxy)-3,4-dihydroisoquinoline hydrochloride
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| Drug Type |
Small molecular drug
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| Indication | Angina pectoris [ICD-11: BA40; ICD-9: 413] | Phase 3 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C26H36ClNO4
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| Canonical SMILES |
CCOC1=C(C=C(C=C1)CC2=NCCC3=CC(=C(C=C32)OC(C)C)OC(C)C)OCC.Cl
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| InChI |
1S/C26H35NO4.ClH/c1-7-28-23-10-9-19(14-24(23)29-8-2)13-22-21-16-26(31-18(5)6)25(30-17(3)4)15-20(21)11-12-27-22;/h9-10,14-18H,7-8,11-13H2,1-6H3;1H
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| InChIKey |
AWQPJKUSDUHYIX-UHFFFAOYSA-N
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| CAS Number |
CAS 69373-88-2
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium channel unspecific (CaC) | Target Info | Antagonist | [2], [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Diproteverine (BRL 40015): a new type of calcium antagonist with potential antianginal properties. Eur J Pharmacol. 1991 Jan 17;192(3):317-27. | |||
| REF 2 | Prenatal toxicity studies in rats and rabbits with the calcium channel blocker diproteverine. Reprod Toxicol. 1996 Jan-Feb;10(1):43-9. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
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