Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06RKS
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| Former ID |
DNC007971
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| Drug Name |
1-(phenylsulfonyl)butan-2-one
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| Synonyms |
CHEMBL240761; 1-(phenylsulfonyl)-2-butanone; 33597-94-3; 1-(phenylsulfonyl)butan-2-one; SCHEMBL12925480; CTK1B8309; DTXSID40452605; 2-Butanone, 1-(phenylsulfonyl)-; BDBM50212545
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H12O3S
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| Canonical SMILES |
CCC(=O)CS(=O)(=O)C1=CC=CC=C1
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| InChI |
1S/C10H12O3S/c1-2-9(11)8-14(12,13)10-6-4-3-5-7-10/h3-7H,2,8H2,1H3
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| InChIKey |
SMYSSDAIMUTBFY-UHFFFAOYSA-N
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| CAS Number |
CAS 33597-94-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolism of xenobiotics by cytochrome P450 | ||||
| Metabolic pathways | ||||
| Chemical carcinogenesis | ||||
| NetPath Pathway | IL1 Signaling Pathway | |||
| FSH Signaling Pathway | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| Metabolism of steroid hormones and vitamin D | ||||
| Glucocorticoid & Mineralcorticoid Metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | beta-Keto sulfones as inhibitors of 11beta-hydroxysteroid dehydrogenase type I and the mechanism of action. Bioorg Med Chem. 2007 Jul 1;15(13):4396-405. | |||
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