Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06RPY
|
|||
| Former ID |
DNC004853
|
|||
| Drug Name |
2-[4-(1-Ethyl-propyl)-piperazin-1-yl]-quinoline
|
|||
| Synonyms |
CHEMBL360156; 2-[4-(1-Ethyl-propyl)-piperazin-1-yl]-quinoline; SCHEMBL3971032
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C18H25N3
|
|||
| Canonical SMILES |
CCC(CC)N1CCN(CC1)C2=NC3=CC=CC=C3C=C2
|
|||
| InChI |
1S/C18H25N3/c1-3-16(4-2)20-11-13-21(14-12-20)18-10-9-15-7-5-6-8-17(15)19-18/h5-10,16H,3-4,11-14H2,1-2H3
|
|||
| InChIKey |
FNSKLNDKQPXTIL-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2-(4-alkylpiperazin-1-yl)quinolines as a new class of imidazole-free histamine H3 receptor antagonists. J Med Chem. 2005 Jan 13;48(1):306-11. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.