Drug Information
Drug General Information | Top | |||
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Drug ID |
D06RSD
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Former ID |
DNC010513
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Drug Name |
1-(4-Cyanobenzyl)-5-(4-pyridyl)-1H-imidazole
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Synonyms |
CHEMBL599602; 1-(4-Cyanobenzyl)-5-(4-pyridyl)-1H-imidazole
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H12N4
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Canonical SMILES |
C1=CC(=CC=C1CN2C=NC=C2C3=CC=NC=C3)C#N
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InChI |
1S/C16H12N4/c17-9-13-1-3-14(4-2-13)11-20-12-19-10-16(20)15-5-7-18-8-6-15/h1-8,10,12H,11H2
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InChIKey |
JQIVWNYGSDPIRG-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Mineralocorticoid biosynthesis | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Pathwhiz Pathway | Steroidogenesis | |||
Reactome | Glucocorticoid biosynthesis | |||
Endogenous sterols | ||||
WikiPathways | Metapathway biotransformation | |||
Oxidation by Cytochrome P450 | ||||
Metabolism of steroid hormones and vitamin D | ||||
Corticotropin-releasing hormone |
References | Top | |||
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REF 1 | Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem. 2010 Feb 25;53(4):1712-25. |
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