Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06TEO
|
|||
| Former ID |
DNC001483
|
|||
| Drug Name |
UCL-1390
|
|||
| Synonyms |
UCL-1390; CHEMBL113030; AC1O4XEX; 4-[3-(1H-Imidazol-4-yl)propoxy]benzonitrile; SCHEMBL650642; XQNBJFUWFIHAMW-UHFFFAOYSA-N; ZINC1536439; BDBM50053278; 4-[3-(1H-imidazol-5-yl)propoxy]benzonitrile; 4-[3-(1H-Imidazol-4-yl)-propoxy]-benzonitrile; L009128; 4-[3-(1H-Imidazol-4-yl)-propoxy]-benzonitrile (UCL 1390)
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Eating disorder [ICD-11: 6B82] | Terminated | [1] | |
| Epilepsy [ICD-11: 8A60-8A68] | Terminated | [1] | ||
| Pain [ICD-11: MG30-MG3Z] | Terminated | [1] | ||
| Therapeutic Class |
Analgesics
|
|||
| Company |
University College London
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C13H13N3O
|
|||
| Canonical SMILES |
C1=CC(=CC=C1C#N)OCCCC2=CN=CN2
|
|||
| InChI |
1S/C13H13N3O/c14-8-11-3-5-13(6-4-11)17-7-1-2-12-9-15-10-16-12/h3-6,9-10H,1-2,7H2,(H,15,16)
|
|||
| InChIKey |
XQNBJFUWFIHAMW-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Antagonist | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005172) | |||
| REF 2 | Emerging drugs for eating disorder treatment. Expert Opin Emerg Drugs. 2006 May;11(2):315-36. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.