Drug Information
Drug General Information | Top | |||
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Drug ID |
D06UZS
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Former ID |
DIB001750
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Drug Name |
VDA-1124
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Synonyms |
Granzyme B inhibitors (abdominal aortic aneurysms), viDA Therapeutics
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Indication | Aortic aneurysm [ICD-11: BD50] | Investigative | [1] | |
Company |
ViDA Therapeutics Inc
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Target and Pathway | Top | |||
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Target(s) | Granzyme B (GZMB) | Target Info | Inhibitor | [1] |
KEGG Pathway | Natural killer cell mediated cytotoxicity | |||
Type I diabetes mellitus | ||||
Transcriptional misregulation in cancer | ||||
Autoimmune thyroid disease | ||||
Allograft rejection | ||||
Graft-versus-host disease | ||||
NetPath Pathway | IL9 Signaling Pathway | |||
TCR Signaling Pathway | ||||
IL2 Signaling Pathway | ||||
IL4 Signaling Pathway | ||||
Panther Pathway | Apoptosis signaling pathway | |||
Pathway Interaction Database | IL12-mediated signaling events | |||
Caspase Cascade in Apoptosis | ||||
Downstream signaling in naï | ||||
Reactome | NOTCH2 intracellular domain regulates transcription | |||
WikiPathways | Oxidative phosphorylation | |||
Signaling by NOTCH2 | ||||
Apoptosis | ||||
Allograft Rejection | ||||
Intrinsic Pathway for Apoptosis |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2369). |
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