Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06VXY
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| Former ID |
DIB015899
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| Drug Name |
SB-237376
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| Synonyms |
SB-237376; UNII-JED8M29NSU; JED8M29NSU; CHEMBL184461; SB-237376 free base; SCHEMBL6737235; XEAKAKKNLOUHDV-UHFFFAOYSA-N; BDBM50151854; n-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-4-nitrobenzamide; N-{3-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-propyl}-4-nitro-benzamide; Benzamide, N-(3-((2-(3,4-dimethoxyphenyl)ethyl)amino)propyl)-4-nitro-
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| Drug Type |
Small molecular drug
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| Indication | Arrhythmia [ICD-11: BC9Z; ICD-9: 427] | Terminated | [1] | |
| Company |
SmithKline Beecham plc
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| Structure |
 |
Download2D MOL |
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| Formula |
C20H25N3O5
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| Canonical SMILES |
COC1=C(C=C(C=C1)CCNCCCNC(=O)C2=CC=C(C=C2)[N+](=O)[O-])OC
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| InChI |
1S/C20H25N3O5/c1-27-18-9-4-15(14-19(18)28-2)10-13-21-11-3-12-22-20(24)16-5-7-17(8-6-16)23(25)26/h4-9,14,21H,3,10-13H2,1-2H3,(H,22,24)
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| InChIKey |
XEAKAKKNLOUHDV-UHFFFAOYSA-N
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| CAS Number |
CAS 179258-59-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium channel unspecific (CaC) | Target Info | Modulator | [1] |
| Potassium channel unspecific (KC) | Target Info | Modulator | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Electrophysiologic effects of SB-237376: a new antiarrhythmic compound with dual potassium and calcium channel blocking action. J Cardiovasc Pharmacol. 2003 Mar;41(3):414-21. | |||
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