Drug Information
Drug General Information | Top | |||
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Drug ID |
D07AKD
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Former ID |
DIB013183
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Drug Name |
TOL-101
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Synonyms |
MAb (transplant rejection), Tolera Therapeutics; Monoclonal antibody (transplant rejection), Tolera Therapeutics; Anti-TCR alpha/beta antibody (transplant rejection/type 1 diabetes/multiple sclerosis), Tolera
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Drug Type |
Antibody
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Indication | Multiple sclerosis [ICD-11: 8A40; ICD-9: 340] | Phase 1/2 | [1] | |
Company |
Tolera Therapeutics Inc
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Target and Pathway | Top | |||
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Target(s) | T-cell receptor (TCR) | Target Info | . | [2] |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT01154387) Evaluating Safety and Efficacy of TOL101 Induction Versus Anti-Thymocyte Globulin to Prevent Kidney Transplant Rejection. U.S. National Institutes of Health. | |||
REF 2 | First-in-Human Study of the Safety and Efficacy of TOL101 Induction to Prevent Kidney Transplant Rejection. Am J Transplant. 2014 June; 14(6): 1346-1355. |
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