Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07DGI
|
|||
| Former ID |
DNC002785
|
|||
| Drug Name |
Glycinamide Ribonucleotide
|
|||
| Synonyms |
Glycineamide ribonucleotide; Glycineamideribotide; glycinamide ribonucleotide; 10074-18-7; 5'-phosphoribosylglycineamide; GAR; 5'-phosphoribosylglycinamide; N1-(5-Phospho-D-ribosyl)glycinamide; {[(2R,3S,4R,5R)-5-(2-aminoacetamido)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid; N1-(5-phospho-beta-D-ribosyl)glycinamide; Glycineamide ribotide; AC1Q5JNA; AC1L4OGM; n-glycyl-5-o-phosphono-; A-d-ribofuranosylamine; 5'-Phosphoribosyl-glycineamide; SCHEMBL4366354; BDBM22589; DTXSID70143478; C03838
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C7H15N2O8P
|
|||
| Canonical SMILES |
C(C1C(C(C(O1)NC(=O)CN)O)O)OP(=O)(O)O
|
|||
| InChI |
1S/C7H15N2O8P/c8-1-4(10)9-7-6(12)5(11)3(17-7)2-16-18(13,14)15/h3,5-7,11-12H,1-2,8H2,(H,9,10)(H2,13,14,15)/t3-,5-,6-,7-/m1/s1
|
|||
| InChIKey |
OBQMLSFOUZUIOB-SHUUEZRQSA-N
|
|||
| CAS Number |
CAS 10074-18-7
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glycinamide ribonucleotide formyltransferase (GART) | Target Info | Inhibitor | [1] |
| BioCyc | Purine nucleotides de novo biosynthesis | |||
| 5-aminoimidazole ribonucleotide biosynthesis | ||||
| Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate | ||||
| KEGG Pathway | Purine metabolism | |||
| One carbon pool by folate | ||||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | De novo purine biosynthesis | |||
| Pathwhiz Pathway | Purine Metabolism | |||
| Reactome | Purine ribonucleoside monophosphate biosynthesis | |||
| WikiPathways | One Carbon Metabolism | |||
| Metabolism of nucleotides | ||||
| Folate Metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.