Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07EJK
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| Former ID |
DNC010511
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| Drug Name |
1-(4-Cyanobenzyl)-5-formyl-1H-imidazole
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| Synonyms |
183500-37-0; CHEMBL611680; 4-(5-formylimidazol-1-ylmethyl)benzonitrile; 4-[(5-formyl-1H-imidazol-1-yl)methyl]benzonitrile; 4-(5-FORMYL-IMIDAZOL-1-YLMETHYL)-BENZONITRILE; 4-((5-formyl-1h-imidazol-1-yl)methyl)benzonitrile; 1-(4-Cyanobenzyl)-5-formyl-1H-imidazole; SCHEMBL1064258; CTK4D8501; DTXSID30442752; AMUOEEKBBOOOCV-UHFFFAOYSA-N; ZINC39118604; BDBM50307239; 1-(4-cyanobenzyl)-5-formylimidazole; AKOS015911901; ACM183500370; SC-55448; KB-238611; FT-0714561; 1-(4-cyanobenzyl)-5-imidazolecarboxaldehyde
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H9N3O
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| Canonical SMILES |
C1=CC(=CC=C1CN2C=NC=C2C=O)C#N
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| InChI |
1S/C12H9N3O/c13-5-10-1-3-11(4-2-10)7-15-9-14-6-12(15)8-16/h1-4,6,8-9H,7H2
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| InChIKey |
AMUOEEKBBOOOCV-UHFFFAOYSA-N
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| CAS Number |
CAS 183500-37-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem. 2010 Feb 25;53(4):1712-25. | |||
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