Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07EQF
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| Former ID |
DNC004241
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| Drug Name |
V-102862
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| Synonyms |
CO 102862; UNII-0KN11H90GF; 181144-66-1; V-102862; CHEMBL287833; 0KN11H90GF; 4-(4-fluorophenoxy)benzaldehyde semicarbazone; (E)-2-(4-(4-fluorophenoxy)benz-ylidene)hydrazinecarboxamide; V102862; 2-(4-(4-Fluorophenoxy)benzylidene)hydrazinecarboxamide; 2-((4-(4-Fluorophenoxy)phenyl)methylene)hydrazinecarboxamide; CO-102862; 2-[[4-(4-Fluorophenoxy)phenyl]methylene]hydrazinecarboxamide; Hydrazinecarboxamide, 2-((4-(4-fluorophenoxy)phenyl)methylene)-; CHEBI:92156; MolPort-022-863-701; BDBM50141073; AKOS016004881; NCGC00167807-01
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C14H12FN3O2
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| Canonical SMILES |
C1=CC(=CC=C1C=NNC(=O)N)OC2=CC=C(C=C2)F
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| InChI |
1S/C14H12FN3O2/c15-11-3-7-13(8-4-11)20-12-5-1-10(2-6-12)9-17-18-14(16)19/h1-9H,(H3,16,18,19)/b17-9+
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| InChIKey |
MHUUDVZSPFRUSK-RQZCQDPDSA-N
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| CAS Number |
CAS 181144-66-1
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:92156
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated sodium channel alpha Nav1.4 (SCN4A) | Target Info | Inhibitor | [1] |
| Voltage-gated sodium channel alpha Nav1.7 (SCN9A) | Target Info | Inhibitor | [2] | |
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 3-(4-phenoxyphenyl)pyrazoles: a novel class of sodium channel blockers. J Med Chem. 2004 Mar 11;47(6):1547-52. | |||
| REF 2 | Substituted biaryl oxazoles, imidazoles, and thiazoles as sodium channel blockers. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5536-40. | |||
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