Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07FVL
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| Former ID |
DNC011989
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| Drug Name |
Oxazolidin-(2Z)-ylideneamine
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| Synonyms |
24665-93-8; amino oxazoline; 1,3-oxazolidin-2-imine; 4,5-dihydrooxazol-2-amine; Oxazolidin-(2Z)-ylideneamine; 2-oxazolamine, 4,5-dihydro-; 4,5-dihydro-1,3-oxazol-2-amine; CHEMBL69446; aminooxazoline; iminooxazolidine; NSC43138; 2-amino-2-oxazoline; AC1Q4UHD; AC1L61HW; 2-amino-4,5-dihydrooxazole; 2-Oxazolamine,4,5-dihydro-; CTK4F4142; DTXSID50285885; MolPort-023-198-771; YAXGBZDYGZBRBQ-UHFFFAOYSA-N; MolPort-006-013-450; BDBM50078037; NSC-43138; ZINC13588690; AKOS006221228; AKOS009159127; NE22687; MCULE-9912511107; AJ-64218; AJ-64217
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C3H6N2O
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| Canonical SMILES |
C1COC(=N1)N
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| InChI |
1S/C3H6N2O/c4-3-5-1-2-6-3/h1-2H2,(H2,4,5)
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| InChIKey |
YAXGBZDYGZBRBQ-UHFFFAOYSA-N
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| CAS Number |
CAS 24665-93-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nitric-oxide synthase inducible (NOS2) | Target Info | Inhibitor | [1] |
| BioCyc | Citrulline-nitric oxide cycle | |||
| KEGG Pathway | Arginine biosynthesis | |||
| Arginine and proline metabolism | ||||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| HIF-1 signaling pathway | ||||
| Peroxisome | ||||
| Salmonella infection | ||||
| Pertussis | ||||
| Leishmaniasis | ||||
| Chagas disease (American trypanosomiasis) | ||||
| Toxoplasmosis | ||||
| Amoebiasis | ||||
| Tuberculosis | ||||
| Pathways in cancer | ||||
| Small cell lung cancer | ||||
| NetPath Pathway | IL1 Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| Pathway Interaction Database | IL12-mediated signaling events | |||
| Alpha9 beta1 integrin signaling events | ||||
| ATF-2 transcription factor network | ||||
| IL23-mediated signaling events | ||||
| Signaling mediated by p38-alpha and p38-beta | ||||
| HIF-1-alpha transcription factor network | ||||
| Reactome | ROS production in response to bacteria | |||
| Nitric oxide stimulates guanylate cyclase | ||||
| WikiPathways | Type II interferon signaling (IFNG) | |||
| Spinal Cord Injury | ||||
| AGE/RAGE pathway | ||||
| Effects of Nitric Oxide | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 4,5-Disubstituted-1,3-oxazolidin-2-imine derivatives: a new class of orally bioavailable nitric oxide synthase inhibitor. Bioorg Med Chem Lett. 2004 Jan 19;14(2):313-6. | |||
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