Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07IEF
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| Former ID |
DIB004848
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| Drug Name |
Bisacodyl
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| Synonyms |
bisacodyl; 603-50-9; Dulcolax; Bicol; Durolax; Brocalax; Stadalax; Sanvacual; Hillcolax; Fenilaxan; Endokolat; Theralax; Dulcolan; Nigalax; Laxorex; Laxadin; Neolax; Laxine; Ivilax; Eulaxan; Ulcolax; Telemin; Laxans; Godalax; Zetrax; Pyrilax; Sk-bisacodyl; Laxanin N; Bisacodylum; Bisacodilo; Deficol; LACO; LA96a; Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester); HalfLytely; Bisacodylum [INN-Latin]; Bisacodilo [INN-Spanish]; (Pyridin-2-ylmethylene)bis(4,1-phenylene) diacetate; Bis(p-acetoxyphenyl)-2-pyridylmethane
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| Drug Type |
Small molecular drug
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| Indication | Constipation [ICD-11: DD91.1; ICD-10: K59.0; ICD-9: 564] | Approved | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C22H19NO4
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| Canonical SMILES |
CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC(=O)C)C3=CC=CC=N3
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| InChI |
1S/C22H19NO4/c1-15(24)26-19-10-6-17(7-11-19)22(21-5-3-4-14-23-21)18-8-12-20(13-9-18)27-16(2)25/h3-14,22H,1-2H3
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| InChIKey |
KHOITXIGCFIULA-UHFFFAOYSA-N
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| CAS Number |
CAS 603-50-9
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:3125
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| ADReCS Drug ID | BADD_D00276 | |||
| Interaction between the Drug and Microbe | Top | |||
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| The Metabolism of Drug Affected by Studied Microbe(s) | ||||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Bacteroidales | ||||
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Studied Microbe: Alistipes indistinctus DSM22520
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Alistipes indistinctus DSM22520 (log2FC = -6.438; p = 0.001). | |||
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Studied Microbe: Bacteroides caccae ATCC 43185
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides caccae ATCC 43185 (log2FC = -11.102; p = 0.001). | |||
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Studied Microbe: Bacteroides cellulosilyticus DSM 14838
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides cellulosilyticus DSM 14838 (log2FC = -6.989; p = 0.001). | |||
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Studied Microbe: Bacteroides coprophilus DSM 18228
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides coprophilus DSM 18228 (log2FC = -9.863; p = 0.004). | |||
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Studied Microbe: Bacteroides dorei DSM 17855
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides dorei DSM 17855 (log2FC = -10.091; p = 0.001). | |||
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Studied Microbe: Bacteroides eggerthii DSM20697
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides eggerthii DSM20697 (log2FC = -10.878; p = 0.001). | |||
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Studied Microbe: Bacteroides finegoldii DSM17565
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides finegoldii DSM17565 (log2FC = -6.5; p = 0.001). | |||
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Studied Microbe: Bacteroides fragilis ATCC43859
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides fragilis ATCC43859 (log2FC = -11.127; p = 0.001). | |||
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Studied Microbe: Bacteroides fragilis HMW 610
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides fragilis HMW 610 (log2FC = -10.467; p = 0.001). | |||
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Studied Microbe: Bacteroides fragilis HMW 615
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides fragilis HMW 615 (log2FC = -10.69; p = 0.001). | |||
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Studied Microbe: Bacteroides fragilis NCTC 9343
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides fragilis NCTC 9343 (log2FC = -9.549; p = 0.001). | |||
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Studied Microbe: Bacteroides fragilis str. 3397 T10
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides fragilis str. 3397 T10 (log2FC = -10.531; p = 0.001). | |||
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Studied Microbe: Bacteroides fragilis str. 3986 T(B)9
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides fragilis str. 3986 T(B)9 (log2FC = -10.349; p = 0.001). | |||
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Studied Microbe: Bacteroides fragilis str. DS-208
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides fragilis str. DS-208 (log2FC = -10.329; p = 0.001). | |||
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Studied Microbe: Bacteroides intestinalis DSM 17393
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides intestinalis DSM 17393 (log2FC = -6.712; p = 0.007). | |||
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Studied Microbe: Bacteroides ovatus ATCC 8483
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides ovatus ATCC 8483 (log2FC = -10.639; p = 0.001). | |||
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Studied Microbe: Bacteroides stercoris ATCC 43183
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides stercoris ATCC 43183 (log2FC = -11.41; p = 0.001). | |||
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Studied Microbe: Bacteroides thetaiotaomicron 3731
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides thetaiotaomicron 3731 (log2FC = -10.412; p = 0.001). | |||
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Studied Microbe: Bacteroides thetaiotaomicron 7330
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides thetaiotaomicron 7330 (log2FC = -10.394; p = 0.001). | |||
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Studied Microbe: Bacteroides thetaiotaomicron VPI-5482
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides thetaiotaomicron VPI-5482 (log2FC = -10.462; p = 0.001). | |||
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Studied Microbe: Bacteroides uniformis ATCC 8492
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides uniformis ATCC 8492 (log2FC = -11.23; p = 0.001). | |||
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Studied Microbe: Bacteroides vulgatus ATCC 8482
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides vulgatus ATCC 8482 (log2FC = -12.105; p = 0.001). | |||
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Studied Microbe: Bacteroides WH2
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides WH2 (log2FC = -8.33; p = 0.001). | |||
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Studied Microbe: Bacteroides xylanisolvens DSM18836
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides xylanisolvens DSM18836 (log2FC = -8.863; p = 0.001). | |||
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Studied Microbe: Odoribacter splanchnicus
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Odoribacter splanchnicus (log2FC = -6.678; p = 0.008). | |||
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Studied Microbe: Parabacteroides distasonis ATCC 8503
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Parabacteroides distasonis ATCC 8503 (log2FC = -7.324; p = 0.032). | |||
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Studied Microbe: Parabacteroides johnsonii DSM 18315
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Parabacteroides johnsonii DSM 18315 (log2FC = -7.186; p = 0.001). | |||
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Studied Microbe: Parabacteroides merdae ATCC 43184
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Parabacteroides merdae ATCC 43184 (log2FC = -5.854; p = 0.001). | |||
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Studied Microbe: Pretovella copri DSM 18205
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Pretovella copri DSM 18205 (log2FC = -11.456; p = 0.001). | |||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Bifidobacteriales | ||||
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Studied Microbe: Bifidobacterium adolescentis ATCC 15703
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bifidobacterium adolescentis ATCC 15703 (log2FC = -9.813; p = 0.002). | |||
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Studied Microbe: Bifidobacterium breve DSM 20213
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bifidobacterium breve DSM 20213 (log2FC = -8.49; p = 0.006). | |||
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Studied Microbe: Bifidobacterium longum subsp. Infantis CCUG52486
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bifidobacterium longum subsp. Infantis CCUG52486 (log2FC = -11.328; p = 0.001). | |||
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Studied Microbe: Bifidobacterium ruminantium
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bifidobacterium ruminantium (log2FC = -8.369; p = 0.002). | |||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Coriobacteriales | ||||
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Studied Microbe: Collinsella aerofaciens ATCC25986
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Collinsella aerofaciens ATCC25986 (log2FC = -10.313; p = 0.004). | |||
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Studied Microbe: Collinsella intestinalis DSM 13280
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Collinsella intestinalis DSM 13280 (log2FC = -1.266; p = 0.002). | |||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Eggerthellales | ||||
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Studied Microbe: Eggerthella lenta ATCC 25559
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Eggerthella lenta ATCC 25559 (log2FC = -1.735; p = 0.006). | |||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Enterobacterales | ||||
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Studied Microbe: Edwardsiella tarda ATCC 23685
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Edwardsiella tarda ATCC 23685 (log2FC = -1.422; p = 0.002). | |||
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Studied Microbe: Enterobacter cancerogenus ATCC35316
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Enterobacter cancerogenus ATCC35316 (log2FC = -0.728; p = 0.031). | |||
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Studied Microbe: Escherichia coli BW25113
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Escherichia coli BW25113 (log2FC = -1.027; p = 0.01). | |||
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Studied Microbe: Proteus penneri ATCC 35198
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Proteus penneri ATCC 35198 (log2FC = -3.918; p = 0.003). | |||
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Studied Microbe: Providencia alcalifaciens DSM 30120
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Providencia alcalifaciens DSM 30120 (log2FC = -10.472; p = 0.0). | |||
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Studied Microbe: Providencia rettgeri DSM 1131
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Providencia rettgeri DSM 1131 (log2FC = -7.201; p = 0.002). | |||
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Studied Microbe: Providencia stuartii ATCC 25827
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Providencia stuartii ATCC 25827 (log2FC = -7.452; p = 0.006). | |||
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Studied Microbe: Salmonella typhimurium LT2
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Salmonella typhimurium LT2 (log2FC = -2.5; p = 0.003). | |||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Erysipelotrichales | ||||
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Studied Microbe: Clostridium ramosum DSM 1402
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Clostridium ramosum DSM 1402 (log2FC = -10.233; p = 0.002). | |||
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Studied Microbe: Clostridium spiroforme DSM1552
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Clostridium spiroforme DSM1552 (log2FC = -10.686; p = 0.004). | |||
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Studied Microbe: Eubacterium biforme DSM 3989
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Eubacterium biforme DSM 3989 (log2FC = -2.176; p = 0.001). | |||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Eubacteriales | ||||
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Studied Microbe: Anaerostipes sp.
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Anaerostipes sp. (log2FC = -9.204; p = 0.003). | |||
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Studied Microbe: Anaerotruncus colihominis DSM 17241
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Anaerotruncus colihominis DSM 17241 (log2FC = -6.431; p = 0.007). | |||
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Studied Microbe: Bacteroides pectinophilus ATCC 43243
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bacteroides pectinophilus ATCC 43243 (log2FC = -10.654; p = 0.002). | |||
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Studied Microbe: Blautia hansenii DSM20583
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Blautia hansenii DSM20583 (log2FC = -1.22; p = 0.002). | |||
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Studied Microbe: Blautia luti DSM 14534
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Blautia luti DSM 14534 (log2FC = -7.587; p = 0.003). | |||
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Studied Microbe: Bryantia formatexigens DSM 14469
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Bryantia formatexigens DSM 14469 (log2FC = -6.339; p = 0.005). | |||
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Studied Microbe: Clostridium asparagiforme DSM 15981
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Clostridium asparagiforme DSM 15981 (log2FC = -6.716; p = 0.002). | |||
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Studied Microbe: Clostridium difficile 120
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Clostridium difficile 120 (log2FC = -9.146; p = 0.006). | |||
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Studied Microbe: Clostridium hathewayi DSM 13479
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Clostridium hathewayi DSM 13479 (log2FC = -10.466; p = 0.002). | |||
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Studied Microbe: Clostridium scindens ATCC 35704
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Clostridium scindens ATCC 35704 (log2FC = -0.918; p = 0.005). | |||
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Studied Microbe: Clostridium sp.
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Clostridium sp. (log2FC = -4.378; p = 0.005). | |||
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Studied Microbe: Clostridium sporogenes ATCC 15579
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Clostridium sporogenes ATCC 15579 (log2FC = -9.324; p = 0.027). | |||
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Studied Microbe: Clostridium symbiosum ATCC 14940
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Clostridium symbiosum ATCC 14940 (log2FC = -6.718; p = 0.004). | |||
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Studied Microbe: Coprococcus comes ATCC 27758
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Coprococcus comes ATCC 27758 (log2FC = -1.584; p = 0.003). | |||
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Studied Microbe: Dorea formicigenerans ATCC 27755
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Dorea formicigenerans ATCC 27755 (log2FC = -1.311; p = 0.007). | |||
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Studied Microbe: Enterocloster bolteae ATCC BAA-613
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Enterocloster bolteae ATCC BAA-613 (log2FC = -4.122; p = 0.004). | |||
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Studied Microbe: Eubacterium hallii DSM3353
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Eubacterium hallii DSM3353 (log2FC = -6.081; p = 0.001). | |||
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Studied Microbe: Eubacterium rectale ATCC 33656
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Eubacterium rectale ATCC 33656 (log2FC = -2.0; p = 0.005). | |||
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Studied Microbe: Eubacterium ventriosum ATCC 27560
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Eubacterium ventriosum ATCC 27560 (log2FC = -5.255; p = 0.005). | |||
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Studied Microbe: Roseburia intestinalis L1-82
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Roseburia intestinalis L1-82 (log2FC = -8.506; p = 0.009). | |||
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Studied Microbe: Ruminococcus gnavus ATCC 29149
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Ruminococcus gnavus ATCC 29149 (log2FC = -6.752; p = 0.003). | |||
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Studied Microbe: Ruminococcus lactaris ATCC 29176
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Ruminococcus lactaris ATCC 29176 (log2FC = -4.885; p = 0.004). | |||
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Studied Microbe: Ruminococcus torques ATCC 27756
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Ruminococcus torques ATCC 27756 (log2FC = -10.122; p = 0.008). | |||
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Studied Microbe: Subdoligranulum variabile DSM 15176
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Subdoligranulum variabile DSM 15176 (log2FC = -1.708; p = 0.001). | |||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Lactobacillales | ||||
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Studied Microbe: Enterococcus faecalis V583
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Enterococcus faecalis V583 (log2FC = -7.482; p = 0.012). | |||
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Studied Microbe: Lactobacillus reuteri CF48-3A
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Lactobacillus reuteri CF48-3A (log2FC = -1.547; p = 0.003). | |||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Tissierellales | ||||
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Studied Microbe: Anaerococcus hydrogenalis DSM 7454
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Anaerococcus hydrogenalis DSM 7454 (log2FC = -5.173; p = 0.005). | |||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Verrucomicrobiales | ||||
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Studied Microbe: Akkermansia muciniphila ATCC BAA-835
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Akkermansia muciniphila ATCC BAA-835 (log2FC = -10.192; p = 0.001). | |||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Victivallales | ||||
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Studied Microbe: Victivallis vadensis ATCC BAA-548
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[2] | |||
| Hierarchy | ||||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by Victivallis vadensis ATCC BAA-548 (log2FC = -5.213; p = 0.001). | |||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Gut microbiota | ||||
| Studied Microbe: Gut microbiota unspecific | [3] | |||
| Experimental Method | High-throughput screening | |||
| Description | Bisacodyl can be metabolized by gut microbiota. | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Mapping human microbiome drug metabolism by gut bacteria and their genes. Nature. 2019 Jun;570(7762):462-467. | |||
| REF 3 | Personalized Mapping of Drug Metabolism by the Human Gut Microbiome. Cell. 2020 Jun 25;181(7):1661-1679.e22. | |||
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