Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D07JCO
|
|||
Former ID |
DNC005743
|
|||
Drug Name |
3-Imidazol-1-yl-quinoline
|
|||
Synonyms |
3-Imidazol-1-yl-quinoline; MLS003269485; SCHEMBL4514468; CHEMBL193556; BDBM8919; 3-(1h-imidazol-1-yl)quinoline; 3-(1H-Imidazole-1-yl)quinoline; Imidazole-substituted quinoline 26; ZINC13674486; Quinoline, 3-(1H-imidazol-1-yl)-; 63822-85-5
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C12H9N3
|
|||
Canonical SMILES |
C1=CC=C2C(=C1)C=C(C=N2)N3C=CN=C3
|
|||
InChI |
1S/C12H9N3/c1-2-4-12-10(3-1)7-11(8-14-12)15-6-5-13-9-15/h1-9H
|
|||
InChIKey |
SRUVTPIFNUPTIR-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Mineralocorticoid biosynthesis | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Pathwhiz Pathway | Steroidogenesis | |||
Reactome | Glucocorticoid biosynthesis | |||
Endogenous sterols | ||||
WikiPathways | Metapathway biotransformation | |||
Oxidation by Cytochrome P450 | ||||
Metabolism of steroid hormones and vitamin D | ||||
Corticotropin-releasing hormone |
References | Top | |||
---|---|---|---|---|
REF 1 | Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart fa... J Med Chem. 2005 Oct 20;48(21):6632-42. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.