Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07JJS
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| Former ID |
DAP001202
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| Drug Name |
Sulfamethizole
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| Synonyms |
Ayerlucil; Famet; Lucosil; Methazol; Microsul; Proklar; Renasul; Rufol; SULFAMETHIAZOLE; Salimol; Solfametizolo; Sulamethizole; Sulfamethazole; Sulfamethizol; Sulfamethizolum; Sulfamethylthiadiazole; Sulfametizol; Sulfapyelon; Sulfstat; Sulfurine; Sulphamethizole; Sulphamethyltiadiazole; Tetracid; Thidicur;Thiosulfil; Ultrasul; Urocydal; Urodiaton; Urolucosil; Urosulfin; Uroz; Solfametizolo [DCIT]; Sulfa gram; Thiosulfil Forte; RP 2145; VK 53; Sulfamethizolum [INN-Latin]; Sulfametizol [INN-Spanish]; Thiosulfil (TN); Sulfamethizole [USAN:INN:JAN]; Thiosulfil-A-Forte; Sulfamethizole (JP15/USP/INN); N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide; N(1)-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide; N(sup 1)-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide; N(sup 1)-(5-Methyl-1,3,4-thiadiazol-2-yl)-sulfanilamide; 2-(p-Aminobenzenesulfonamido)-5-methylthiadiazole; 2-Methyl-5-sulfanilamido-1,3,4-thiadiazole; 2-Sulfanilamido-5-methyl-1,3,4-thiadiazole; 4-Amino-N-(5-Methyl-1,3,4-Thiadiazol-2-Yl)Benzene-1-Sulfonamide; 4-Amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide; 4-Amino-N-[5-methyl-1,3,4-thiadiazol-2-yl]benzenesulfonamide; 5-Methyl-2-sulfanilamido-1,3,4-thiadiazole
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| Drug Type |
Small molecular drug
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| Indication | Urinary tract infection [ICD-11: GC08; ICD-10: N39, N39.0; ICD-9: 599] | Approved | [1] | |
| Therapeutic Class |
Antiinfective Agents
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| Structure |
 |
Download2D MOL |
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| Formula |
C9H10N4O2S2
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| Canonical SMILES |
CC1=NN=C(S1)NS(=O)(=O)C2=CC=C(C=C2)N
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| InChI |
1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)
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| InChIKey |
VACCAVUAMIDAGB-UHFFFAOYSA-N
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| CAS Number |
CAS 144-82-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
10250, 856011, 4484560, 7847935, 7980701, 8149536, 8153271, 10321215, 11112301, 11335316, 11360555, 11363886, 11366448, 11369010, 11371560, 11374399, 11377172, 11461527, 11466770, 11467890, 11485179, 11486399, 11489138, 11490386, 11492455, 11494806, 14750528, 17389528, 24870514, 24899662, 26611928, 26679913, 26683918, 26747082, 26747083, 29224382, 46508656, 47290998, 47515174, 47662124, 47736323, 47885267, 47959581, 47959582, 48034964, 48416574, 48424124, 48425641, 49698732, 49855021
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| ChEBI ID |
CHEBI:9331
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| SuperDrug ATC ID |
B05CA04; D06BA04; J01EB02; S01AB01
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| SuperDrug CAS ID |
cas=000144821
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Dihydropteroate synthetase (Bact folP) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many modes of action should an antibiotic have Curr Opin Pharmacol. 2008 Oct;8(5):564-73. | |||
| REF 2 | Inhibition of bioluminescence in Photobacterium phosphoreum by sulfamethizole and its stimulation by thymine. Biochim Biophys Acta. 1990 Jun 26;1017(3):229-34. | |||
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