Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07JMO
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| Former ID |
DNC010497
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| Drug Name |
1-(3-Bromobenzyl)-1H-imidazole
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| Synonyms |
1-(3-Bromobenzyl)-1H-imidazole; 72459-47-3; 1-(3-bromobenzyl)imidazole; CHEMBL598391; 1H-Imidazole,1-[(3-bromophenyl)methyl]-; 1-[(3-bromophenyl)methyl]imidazole; SCHEMBL1848631; CTK5D6138; [(3-bromophenyl)methyl]imidazole; DTXSID00436926; BGYZLOIBJCHCTI-UHFFFAOYSA-N; MolPort-000-143-256; SBB098740; ZINC12370275; BDBM50307216; AKOS013124377; RP05747; KB-63888; 1-[(3-bromophenyl)methyl]-1H-imidazole; AJ-61784; DB-074567; ST24037191; Y9919; FT-0708606; 1-(3-bromobenzyl)-1H-imidazole, AldrichCPR; J-503102; Z1532751877
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C10H9BrN2
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| Canonical SMILES |
C1=CC(=CC(=C1)Br)CN2C=CN=C2
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| InChI |
1S/C10H9BrN2/c11-10-3-1-2-9(6-10)7-13-5-4-12-8-13/h1-6,8H,7H2
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| InChIKey |
BGYZLOIBJCHCTI-UHFFFAOYSA-N
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| CAS Number |
CAS 72459-47-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem. 2010 Feb 25;53(4):1712-25. | |||
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