Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07KNG
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| Former ID |
DNC000465
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| Drug Name |
Costunolide
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| Synonyms |
Costunolide; Costunolid; Costus lactone; Costunlide; AC1NSPGS; HRYLQFBHBWLLLL-GYIATTAWSA-N; Cyclodeca[b]furan-2(3H)-one, 3a,4,5,8,9,11a-hexahydro-6,10-dimethyl-3-methylene-, [3aS-(3aR*,6E,10E,11aS*)]-; BRD-A49888826-001-01-8; (6E,10E)-3a,4,5,8,9,11a-Hexahydro-6,10-dimethyl-3-methylenecyclodeca[b]furan-2(3H)-one; (E,E)-6-.alpha.-Hydroxygermacra-1(10),4,11(13)-trien-12-oic acid .gamma.-lactone; Germacra-1(10),4,11(13)-trien-12-oic acid, 6.alpha.-hydroxy-, .gamma.-lactone, (E,E)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C15H20O2
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| Canonical SMILES |
CC1=CCCC(=CC2C(CC1)C(=C)C(=O)O2)C
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| InChI |
1S/C15H20O2/c1-10-5-4-6-11(2)9-14-13(8-7-10)12(3)15(16)17-14/h5,9,13-14H,3-4,6-8H2,1-2H3/b10-5+,11-9+/t13-,14+/m0/s1
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| InChIKey |
HRYLQFBHBWLLLL-AHNJNIBGSA-N
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| CAS Number |
CAS 553-21-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:3900
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Microtubule-associated protein (MAP) | Target Info | Binder | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A sesquiterpene lactone, costunolide, interacts with microtubule protein and inhibits the growth of MCF-7 cells. Chem Biol Interact. 2004 Jan 15;147(1):79-86. | |||
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