Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07KTP
|
|||
| Former ID |
DNC002364
|
|||
| Drug Name |
SCH79687
|
|||
| Synonyms |
CHEMBL366977; 224585-45-9; SCHEMBL7860131; BDBM86188; DTXSID20430941; SCH 79687; PDSP1_001301; SCH-79687; PDSP2_001285; L018853
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Central nervous system disease [ICD-11: 8A04-8D87; ICD-10: G00-G99] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C18H16Cl2N4O
|
|||
| Canonical SMILES |
C1=CC(=CC=C1CC2=CN=CN2)CNC(=O)NC3=CC(=CC(=C3)Cl)Cl
|
|||
| InChI |
1S/C18H16Cl2N4O/c19-14-6-15(20)8-16(7-14)24-18(25)22-9-13-3-1-12(2-4-13)5-17-10-21-11-23-17/h1-4,6-8,10-11H,5,9H2,(H,21,23)(H2,22,24,25)
|
|||
| InChIKey |
CXNCQFJNXQAFND-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 224585-45-9
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Antagonist | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The histamine H3 receptor: from gene cloning to H3 receptor drugs. Nat Rev Drug Discov. 2005 Feb;4(2):107-20. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.