Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07LWK
|
|||
| Former ID |
DCL000445
|
|||
| Drug Name |
AVE0118
|
|||
| Synonyms |
UNII-Q1B712V03A; AVE-0118; CHEMBL1671897; Q1B712V03A; 498577-53-0; CHDSRMIDIQABTP-UHFFFAOYSA-N; SCHEMBL498292; ZINC3986746; BDBM50417943; SB17438; NCGC00386732-01; (1,1'-Biphenyl)-2-carboxamide, 2'-((((4-methoxyphenyl)acetyl)amino)methyl)-N-(2-(3-pyridinyl)ethyl)-; 2'-((2-(4-Methoxyphenyl)acetylamino)methyl)biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide; (1,1'-Biphenyl)-2-carboxamide, 2'-(((2-(4-methoxyphenyl)acetyl)amino)methyl)-N-(2-(3-pyridinyl)ethyl)-
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Obstructive sleep apnea [ICD-11: 7A41; ICD-9: 327.23, 780.57] | Phase 1 | [1] | |
| Company |
Sanofi-Aventis
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C30H29N3O3
|
|||
| Canonical SMILES |
COC1=CC=C(C=C1)CC(=O)NCC2=CC=CC=C2C3=CC=CC=C3C(=O)NCCC4=CN=CC=C4
|
|||
| InChI |
1S/C30H29N3O3/c1-36-25-14-12-22(13-15-25)19-29(34)33-21-24-8-2-3-9-26(24)27-10-4-5-11-28(27)30(35)32-18-16-23-7-6-17-31-20-23/h2-15,17,20H,16,18-19,21H2,1H3,(H,32,35)(H,33,34)
|
|||
| InChIKey |
CHDSRMIDIQABTP-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 498577-53-0
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Potassium channel unspecific (KC) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019047) | |||
| REF 2 | Neurogenic contraction induced by the antiarrhythmic compound, AVE 0118, in rat small mesenteric arteries.Basic Clin Pharmacol Toxicol.2014 Oct;115(4):315-20. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.