Drug Information
Drug General Information | Top | |||
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Drug ID |
D07MGC
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Drug Name |
Talacotuzumab
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Synonyms |
JNJ 473; JNJ 56022473; TAL
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Indication | Acute myeloid leukaemia [ICD-11: 2A60] | Phase 2 | [1], [2] | |
Company |
Janssen Research & Development Raritan, NJ
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Target and Pathway | Top | |||
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Target(s) | Interleukin 3 receptor alpha (IL3RA) | Target Info | . | [1] |
KEGG Pathway | Cytokine-cytokine receptor interaction | |||
PI3K-Akt signaling pathway | ||||
Apoptosis | ||||
Jak-STAT signaling pathway | ||||
Hematopoietic cell lineage | ||||
NetPath Pathway | IL5 Signaling Pathway | |||
IL3 Signaling Pathway | ||||
Pathway Interaction Database | IL3-mediated signaling events | |||
Reactome | GPVI-mediated activation cascade | |||
G beta:gamma signalling through PI3Kgamma | ||||
Interleukin-3, 5 and GM-CSF signaling | ||||
RAF/MAP kinase cascade | ||||
Interleukin receptor SHC signaling | ||||
WikiPathways | IL-3 Signaling Pathway | |||
Interleukin-2 signaling | ||||
Interleukin-3, 5 and GM-CSF signaling |
References | Top | |||
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REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
REF 2 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) |
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