Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07NKO
|
|||
| Former ID |
DNC004082
|
|||
| Drug Name |
5-[(1R)-1-ammonioethyl]isoxazol-3-olate
|
|||
| Synonyms |
CHEMBL283019; (r)-5-(1-aminoethyl)-3-isoxazolol
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C5H8N2O2
|
|||
| Canonical SMILES |
CC(C1=CC(=O)NO1)N
|
|||
| InChI |
1S/C5H8N2O2/c1-3(6)4-2-5(8)7-9-4/h2-3H,6H2,1H3,(H,7,8)/t3-/m1/s1
|
|||
| InChIKey |
ICRYUJPBYIPXQF-GSVOUGTGSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| GABA(A) receptor alpha-2 (GABRA2) | Target Info | Inhibitor | [1] | |
| GABA(A) receptor alpha-3 (GABRA3) | Target Info | Inhibitor | [1] | |
| GABA(A) receptor alpha-5 (GABRA5) | Target Info | Inhibitor | [1] | |
| GABA(A) receptor beta-2 (GABRB2) | Target Info | Inhibitor | [1] | |
| GABA(A) receptor gamma-2 (GABRG2) | Target Info | Inhibitor | [1] | |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Serotonergic synapse | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| Iron uptake and transport | ||||
| SIDS Susceptibility Pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | gamma-Aminobutyric acid agonists, antagonists, and uptake inhibitors. Design and therapeutic aspects. J Med Chem. 1981 Dec;24(12):1377-83. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.