Drug Information
Drug General Information | Top | |||
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Drug ID |
D07NTN
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Former ID |
DIB012718
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Drug Name |
CERM-11956
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Synonyms |
N-(1,3-Benzodioxolan-5-yl)-N-phenylmethyl-beta-[(2-methylpropoxy)methyl]-1-pyrrolidinylethanamine fumarate; 2-(N-Pyrrolidino)-3-isobutoxy-N-(3,4-methylenedioxyphenyl)-N-benzylpropylamine fumarate
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Drug Type |
Small molecular drug
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Indication | Angina pectoris [ICD-11: BA40; ICD-9: 413] | Discontinued in Phase 1 | [1] | |
Structure |
Download2D MOL |
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Formula |
C29H38N2O7
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Canonical SMILES |
CCC(C)OCC(CN(CC1=CC=CC=C1)C2=CC3=C(C=C2)OCO3)N4CCCC4.C(=CC(=O)O)C(=O)O
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InChI |
1S/C25H34N2O3.C4H4O4/c1-3-20(2)28-18-23(26-13-7-8-14-26)17-27(16-21-9-5-4-6-10-21)22-11-12-24-25(15-22)30-19-29-24;5-3(6)1-2-4(7)8/h4-6,9-12,15,20,23H,3,7-8,13-14,16-19H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
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InChIKey |
RDZJRZMQCVQTSK-WLHGVMLRSA-N
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CAS Number |
CAS 97631-49-7
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Calcium channel unspecific (CaC) | Target Info | Antagonist | [2], [3] |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000166) | |||
REF 2 | The anti-ischaemic activity of the novel compound, CERM 11956, compared with that of bepridil and nifedipine in isolated guinea-pig hearts. Eur J Pharmacol. 1988 May 10;149(3):195-203. | |||
REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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