Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07ODC
|
|||
| Former ID |
DIB016050
|
|||
| Drug Name |
VBY- 036
|
|||
| Synonyms |
VBY-036
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|
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| Indication | Neuropathic pain [ICD-11: 8E43.0] | Phase 1 | [1] | |
| Company |
Virobay
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cathepsin S (CTSS) | Target Info | Inhibitor | [2] |
| KEGG Pathway | Lysosome | |||
| Phagosome | ||||
| Antigen processing and presentation | ||||
| Tuberculosis | ||||
| NetPath Pathway | Leptin Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| Reactome | Endosomal/Vacuolar pathway | |||
| Degradation of the extracellular matrix | ||||
| Trafficking and processing of endosomal TLR | ||||
| Assembly of collagen fibrils and other multimeric structures | ||||
| MHC class II antigen presentation | ||||
| WikiPathways | Class I MHC mediated antigen processing & presentation | |||
| Trafficking and processing of endosomal TLR | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01892891) Safety Study of VBY-036 in Healthy Volunteers After 7 Days of Oral Dosing. U.S. National Institutes of Health. | |||
| REF 2 | Clinical pipeline report, company report or official report of ViroBay. | |||
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