Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07PSG
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| Former ID |
DNC011241
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| Drug Name |
5-phenyl-2-(4-(piperidin-1-yl)butyl)oxazole
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| Synonyms |
CHEMBL1257573; 5-phenyl-2-(4-(piperidin-1-yl)butyl)oxazole
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H24N2O
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| Canonical SMILES |
C1CCN(CC1)CCCCC2=NC=C(O2)C3=CC=CC=C3
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| InChI |
1S/C18H24N2O/c1-3-9-16(10-4-1)17-15-19-18(21-17)11-5-8-14-20-12-6-2-7-13-20/h1,3-4,9-10,15H,2,5-8,11-14H2
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| InChIKey |
XJINDZCEGQZNLD-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Azole derivatives as histamine H3 receptor antagonists, part 2: C-C and C-S coupled heterocycles. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5883-6. | |||
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